Bone regrowth is a challenge in elderly patient and in some diseases with fragilized skeleton. Many new drug devices including bone particles or coral implants and new polymer matrix need to be tested to evaluate therapeutic potential, while osteoporotic treatments need to be improved as well.
Not only at APcis, HD imaging allow to avoid mineralization by ultra high resolution, but VISCOM 2500 may detect variation of osteogenesis in mouse mandibular area. We can calculate volume of root space by image analysis.
Moreover, difficult protocol such as Nature Protocol for bone regenberation, dec 2012, can be performed and recovery measured after 100 days again without demineralization of samples as resolution with our CT scan technique is in the 20-100µm range.